Hydroxychloroquine Sulfate or Hydroxychloroquine Sulphate CAS 747-36-4 China Hydroxychloroquine Sulfate or Hydroxychloroquine Sulphate CAS 747-36-4 factory, Supplier, Manufacturer in China. CAS Number: 747-36-4 Characteristics: Odorless solid powder. Molecular Formula: C18H28ClN3O5S;...
Hydroxychloroquine Sulfate or Hydroxychloroquine Sulphate CAS 747-36-4
China Hydroxychloroquine Sulfate or Hydroxychloroquine Sulphate CAS 747-36-4 factory, Supplier, Manufacturer in China.
CAS Number: 747-36-4
Characteristics: Odorless solid powder.
Molecular Formula: C18H28ClN3O5S; C18H26ClN3O·H2SO4
Package: 25Kgs/Fiber Drum
Transportation mark: 6.1 Class dangerous cargo.
KEY Words: Hydroxychloroquine Sulfate or Hydroxychloroquine Sulphate CAS 747-36-4
Hydroxychloroquine sulfate is used in rheumatoid arthritis, juvenile chronic arthritis, discoid and systemic lupus erythematosus, and skin lesions caused or aggravated by sunlight.
It is an anti malarial drug, which can also be used to reduce the inflammation caused by rheumatoid arthritis and lupus. The difference between Hydroxychloroquine Sulfate and chloroquine is that the end of side chain contains hydroxyl.
The pharmacokinetics of Hydroxychloroquine Sulphate is similar to chloroquine, which can be absorbed rapidly in gastrointestinal tract and excreted in kidney.
Note: Hydroxychloroquine Sulfate is harmful to the environment and pollutes the water body. It is forbidden to enter the water body.
Properties and stability:
1. Avoid contact with incompatible materials and light.
2. Hydroxychloroquine Sulfate reacts with strong oxidant and strong base.
Hydroxychloroquine Sulfate can be used to treat Rheumatoid arthritis, juvenile chronic arthritis, discoid and systemic lupus erythematosus, and skin lesions caused or aggravated by sunlight.
Side effects of Hydroxychloroquine Sulphate:
There are few reports of retinitis pigmentation and visual field defect. These lesions are reversible after early discontinuation of this product. In case of further development, even if the product is stopped, there is still an increased risk. Cases of maculopathy and macular degeneration are reported and may be irreversible.
Although there is no specific report, Hydroxychloroquine Sulfate may also have several drug interactions known for chloroquine. These include aminoglycoside antibiotics, which can enhance the direct blocking effect of neuromuscular junction, cimetidine, which can inhibit its metabolism and increase the plasma concentration of antimalarial drugs, antagonize the effects of neostigmine and pyridoside, and weaken the primary immune antibody response of the body to intradermal injection of human diploid cell rabies vaccine.
Hydroxychloroquine Sulfate has similar pharmacological action, pharmacokinetics and metabolism process with chloroquine. After oral administration, it will be absorbed rapidly and almost completely.
Hydroxychloroquine sulfate is a kind of oral medicine. Its main function is to treat rheumatoid arthritis, lupus erythematosus, young chronic arthritis and so on. It can also treat skin lesions caused by or aggravated by sunlight. The main component of hydroxychloroquine sulfate is aminoquinoline, which is used in the treatment of lupus erythematosus or systemic lupus erythematosus. The mechanism of action is not completely clear. It can apply for examination and interfere with the interaction of enzyme activity, combine with DNA, inhibit the formation of prostaglandins, and also inhibit the chemotaxis and phagocytosis of polymorphonuclear cells. Although the mechanism of hydroxychloroquine sulfate has not been fully understood, it is now believed that the drug may be related to immunosuppression and anti-inflammatory drugs.
At first, it was a kind of anti-malarial drug. Later, it was found that this kind of drug had mild immunosuppressive and immunomodulatory effects. At present, hydroxychloroquine sulfate tablets are widely used in rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, connective tissue disease, Sjogren's syndrome, idiopathic myositis, immune vasculitis, Behcet's disease and many other diseases. In addition, this drug is a basic drug in systemic lupus erythematosus, especially the long-term effect.
Hydroxychloroquine sulfate is also prone to some side effects in the course of taking the drug. According to the drug analysis, it is found that taking hydroxychloroquine sulfate may cause nervous system reactions such as nervous allergy, excitement, mood change, psychosis, dizziness, vertigo, tinnitus, nervous deafness, convulsion, etc.
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